Terminal Differentiation of Human Keratinocytes and Stratum Corneum Formation is Associated with Caspase-14 Activation
نویسندگان
چکیده
منابع مشابه
Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation.
Programmed cell death of epidermal keratinocytes (KC) results in the formation of cornified cells, which constitute the outermost skin layer, the stratum corneum. Here we show by reverse transcription-polymerase chain reaction, western blot, and immunohistochemistry that epidermal KC express caspase-14, a member of the caspase family of pro-apoptotic proteases, in a tissue-specific manner. Casp...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2000
ISSN: 0022-202X
DOI: 10.1046/j.1523-1747.2000.00205.x